Intermediates

Intermediates

API Intermediate Name CAS No
Ramelteon (E)-2-(6,7-dihydro-1H-indeno[5,4- b]furan-8(2H)-ylidene)acetonitrile 196597-79-2
Ramelteon 1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one 196597-78-1
Ramelteon Darifenacin 2,3-dihydro-1-benzofuran 496-16-2
Flurbiprofen 4-bromo-2-fluoro-1,1'-biphenyl 41604-19-7
Vilazodone 5-Aminobenzofuran-2-carboxylic acid ethyl ester 174775-48-5
Bilastine 2-(piperidin-4-yl)-1H-benzo[d]imidazole 38385-95-4
Bilastine 2-ethoxyethyl 4-methylbenzenesulfonate 17178-11-9t
Bilastine 2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1-methylethyl] phenyl]ethyl 4-methylbenzenesulfonate 202189-76-2
Barnepidine (S)-1-benzylpyrrolidin-3-ol 101385-90-4
Posaconazole (S)-(+)-4-Phenyl-2-oxazolidinone 99395-88-7
Posaconazole (R)-(-)-4-Phenyl-2-oxazolidinone 90319-52-1
Azealic Acid Nonanedioic Acid 123-99-9
7-bromo-2,3-dichloropyrido[2,3-b]pyrazine 341939-31-9
Dabigatran ethyl 3-(3-amino-4-(methylamino)-N-(pyridin-2-yl)benzamido)propanoate 341939-31-9
Dabigatran (4-cyanophenyl)glycine 42288-26-6
Dabigatran Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole5-carboxamido)propanoate hydrochloride 341939-31-9
Formamidine acetate Formamidine acetate salt 3473-63-0
Tofacitinib (3R,4R)-1-Benzyl-N,4-dimethyl piperidin-3-amine dihydrochloride 1062580-52-2
Tofacitinib, Oclacitinib 4-chloro-7H-pyrrolo [2,3-d]pyrimidine 3680-69-1
 
Ivacaftor 4-Oxo-1,4-di hydroquinoline-3-carboxylic acid 13721-01-2
Ivacaftor 5-amino-2,4-di-tert-butylphenol 873055-58-4
Fluconazole 1-(2,4-Diflurophenyl)-1-(1H-1,2,4-triazole-1yl)-ethanone (DFTA) 873055-58-4
Voriconazole (2R, 3S/2S, 3R)-3-(5-Fluoropyrimidin-4-yl)-2-(2,4-difluorophyenyl)-1-(1H-1,2,4 triazol-1-yl) butan-2-ol{Racemic Voriconazole} 873055-58-4
Voriconazole ((2R, 3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidine-4yl)-1-(1H-1,2,4 triazol-1-yl) butan-2-ol camphor sulfonate 137234-71-0
Terbinafine Trans-1-Chloro-6,6-dimethylhept-2-en-4-yne 83554-69-2
Terbinafine N-(1-Naphtyl methyl) methyl amine Hydrochloride 65473-13-4
Terbinafine N-(1-Naphtyl methyl) methyl amine Hydrochloride 14489-75-9
Escitalopram Oxalate 4-[(4-Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile Hydrobromide 137234-71-0
Escitalopram Oxalate 4-[(4-Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile D-hemi tartaricacid salt 128173-53-5
Zafirlukast Methyol 4-(5-Amino-1-Methyl Indol-3-yl Methyl)-3-Methoxy Benzoate 107754-14-3
Sumatriptan 4-Hydrazino-N-methylbenzene methane sulfonamide HCL (HMBS) 88933-16-8
Sumatriptan 4-Chlorobutyraldehydesodiumbisulfine (ADDUCT) 54322-20-2
Sumatriptan 4-(N,N-Dimethylamino) butane diethyl acetal 1116-77-4
Zolmitriptan 4-Nitro-L-phenylalanine monhydrate 207591-86-4
Midazolam 2-Amino Methyl-7-Chloro-2,3-Dihydro-5- (2-Fluro Phenyl)1H-1,4-Benzodiazepine Dimaleate 59469-29-3
Midazolam 8-Chloro-6-(2-fluorophenyl)-1-methy-4H-imidazol[1,5-a][1,4]benzodiazepine-3-Carboxylic acid 59468-44-9

Oncology Intermediates

API Intermediate Name CAS No
Pazopanib 2,3-dimethyl-2H-indazol-6-amine Hydrochloride 635702-60-2
Pazopanib N-(2-chloropyrimidin-4-yl)-N, 2,3-trimethyl-2H-indazol-6-amine 444731-75-3
Pazopanib 2,4-Dichloro pyrimidine 3934-20-1
Palbociclib 6-Bromo-2-Chloro-8-cyclopentyl-5-methyl pyrido [2,3-d] pyrimidin -7(8H)-one 1016636-76-2
Palbociclib 1-tert-Butoxy carbonyl-4-(6-amino-3-pyridyl) piperazine 571188-59-5
Osimertinib 3-(2-chloro pyrimidin-4-yl)-1-methyl-1H-indole 1032452-86-0
Osimertinib 4-fluoro-2-methoxy-5-nitro aniline 1075705-01-9
Fedratinib 3-amino-N-(tert-butyl)benzenesulfonamide 608523-94-0
Fedratinib 2-chloro-5-methyl pyrimidin -4-amine 14394-70-8
Olaparib cyclopropyl(piperazin-1-yl)methanone hydrochloride 1021298-67-8
Gefitinib 7-Methoxy-6-(3-morpholinopropoxy) quinazolin-4(3H)-one 199327-61-2
Gefitinib 7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate 179688-53-0
Gefitinib 4-(3-Chloropropyl)morpholine 7357-67-7
Gefitinib 4-methoxy-5-(3-morpholinopropoxy) -2-nitrobenzonitrile 675126-26-8
Gefitinib 5-hydroxy-4-methoxy-2-nitrobenzoic acid 31839-20-0
Gefitinib ethyl 5-hydroxy-4-methoxy-2-nitrobenzoate 1146162-38-0
Gefitinib 4,5-dimethoxy-2-nitrobenzoic acid 4998-07-6
Gefitinib, Afatinib, Neratinib 3-chloro-4-fluoroaniline 367-21-5
Imatinib Masitinib 4-((4-methylpiperazin-1-yl)methyl)benzoic acid dihydrochloride 106261-49-8
Imatinib 6-methyl-N-(5-amino-2-methylpheny)-4-(3-pyridyl)-2-pyrimidine 152460-10-1
 
Copanslib 7-methoxy-8-(3-morpholinopropoxy)-2,3- dihydropyrrolo[1,2-c]quinazolin-5-amine 1032570-74-3
Ibrutinib (R)-tert-butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl) piperidine-1-carboxylate 1022150-11-3
Ibrutinib, Zanubrutinib 5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile 330792-70-6
Ibrutinib,Zanubrutinib €-tert-butyl 4-(3-(dimethylamino)acryloyl) piperidine-1-carboxylate 960201-86-9
Pralsetinib 1-(6-bromopyridin-3-yl)ethan-1-one 139042-59-4
Pemetrexed 4-(2-(2-amino-4-hydroxy-7H-pyrrolo[2,3-d] pyrimidin-5-yl)ethyl)benzoic acid 137281-39-1
Pemetrexed 2,6-diaminopyrimidin-4-ol 56-06-4
Pemetrexed but-3-yn-1-ol 927-74-2
Nintedanib methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1168150-46-6
Nintedanib methyl 2-oxoindoline-6-carboxylate 14192-26-8
Nintedanib N-(4-aminophenyl)-N-methyl-2- (4-methylpiperazin-1-yl)acetamide 262368-30-9
Erlotinibt 4,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile 236750-65-5
Mebocertinibt Isopropyl 2-chloro-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate -NA-
Abemaciclib 5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-amine 1180132-17-5
Abemaciclib 4-fluoro-1-isopropyl-2-methyl-6-(4,4,5,5- tetramethyl-1,3,2- dioxaborolan- 2-yl)-1H-benzo[d]imidazole 1231930-37-2